When preparing for a sacred Ayahuasca journey, you’ll often hear about “the dieta.” It’s easy to see this as a restrictive tradition, but what if we saw it as a bridge between ancient wisdom and modern science, a profound act of self-respect and a biologically intelligent way to prepare your body and mind?
Think of it not as a list of “can’ts,” but as a gentle, intentional way of clearing the temple, your physical and neurological system, so the spirit of the medicine can work with greater clarity, safety, and depth.
Here’s the holistic why, supported by science and shared as compassionate guidance:
The Heart of the Preparation: Safety & Sensitization (Before the Retreat)
The dietary guidelines are rooted in both tradition and essential pharmacology.
The MAOI Science: Ayahuasca contains natural MAOIs (Monoamine Oxidase Inhibitors) from the Banisteriopsis caapi vine. MAOIs require caution with foods high in tyramine (found in aged cheeses, fermented foods, cured meats). When combined, they can cause a dangerous spike in blood pressure (hypertensive crisis). Avoiding these foods isn’t mystical, it’s a critical, evidence-based safety protocol.
Neurological Preparation: Reducing stimulants (caffeine, alcohol) and intoxicants allows your nervous system to regulate its natural dopamine and serotonin levels. This helps prevent overstimulation and supports a clearer baseline, making your mind more receptive and less reactive to the medicine’s profound effects.
During Your Retreat: Nourishment as Neural Support
The meals served during your stay are designed as part of your holistic, biological care.
You’ll be nourished with light, clean, and anti-inflammatory foods, fresh fruits, vegetables, and whole grains. These foods are rich in antioxidants and easy to digest, supporting your body’s innate healing processes.
Why we avoid heavy meats, fats, and processed foods: Digestion is metabolically expensive. A diet low in heavy proteins and saturated fats reduces metabolic load, allowing more of your body’s energy to be directed toward neural processing and emotional integration. Scientifically, this may support the neuroplasticity, the brain’s ability to form new connections, that psychedelics facilitate.
Blood Sugar Stability: Simple, whole-food meals help maintain stable blood glucose levels. This prevents energy crashes and supports balanced mood and focus, which is crucial for navigating deep psychological work.
After Your Ceremony: Integration Through Nourishment
Post-ceremony care is where science and spirit continue to align. Your brain has entered a state of heightened neuroplasticity, a temporary “open window” for learning and change.
Continuing with light, nutrient-dense foods for several days supports this delicate state. Heavy, hard-to-digest foods can divert energy away from this crucial integration process.
Gut-Brain Axis: Reintroducing foods mindfully is key. Your gut microbiome directly influences your mood and cognition via the gut-brain axis. Nourishing it with probiotics (like yogurt, kefir) and prebiotics (like vegetables) after your retreat can positively support your emotional integration and long-term well-being.
This period is a beautiful opportunity to listen to your body’s new wisdom and to make conscious, science-backed choices that support the new neural pathways you are building.
Ultimately, this approach to food is an extension of your intention. It’s a practical, loving, and scientifically-informed way to say to yourself: “I honor this vessel. I prepare this space with care for the sacred and biological work we are about to do together.”
It’s not a test of willpower; it’s the first step in the sacred partnership between you, your body’s chemistry, and the medicine’s wisdom.
Wishing you a journey of deep connection, safety, and gentle care.


